Disorders of the Sympathetic Nervous System [Abstract]

Sympathetic nervous system neuroplasticity.

In human and experimental models of heart failure there is widespread change in the sympathetic nervous system. This involves preferential activation of the sympathetic nervous outflow to the heart, impairment of norepinephrine reuptake by sympathetic nerves, and reduction of the content of norepinephrine in the failing myocardium, attributable in part to sympathetic neuronal rarefaction.1–4 Mi...

The Surgery of the Sympathetic Nervous System

Surgery of the Sympathetic Nervous System

This article reviews the innervation of the arterial system of the lower extremity, lumbar sympathectomy in vascular surgery, lumbar sympathectomy for digital gangrene and in the prevention of major amputation of the lower extremity and substance P's role in neurogenic inflammatory modulation. Long-term results of lumbar sympathectomy and direct arterial bypass surgery have also been reviewed. ...

Sympathetic nervous system and hypertension.

Sympathetic Nervous System and Hypertension Print ISSN: 0194-911X. Online ISSN: 1524-4563 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Hypertension doi: 10.1161/HYPERTENSIONAHA.111.00633 2013;61:556-560; originally published online January 28, 2013; Hypertension. http://hyper.ahajo...

The sympathetic nervous system and heart failure.

Heart failure (HF) is a syndrome characterized by upregulation of the sympathetic nervous system and abnormal responsiveness of the parasympathetic nervous system. Studies in the 1980s and 1990s demonstrated that inhibition of the renin-angiotensin-aldosterone system with angiotensin-converting enzyme inhibitors improved symptoms and mortality in HF resulting from systolic dysfunction, thus pro...